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Toxic Epidermal Necrolysis Complicating Infliximab Therapy in Refractory Kawasaki Disease

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Author(s)
Abraham KwakSung Ae KimHee Joung Choi
Keimyung Author(s)
Kim, Sung AeChoi, Hee Joung
Department
Dept. of Dermatology (피부과학)
Dept. of Pediatrics (소아청소년학)
Journal Title
Keimyung Medical Journal
Issued Date
2020
Volume
39
Issue
2
Keyword
InfliximabKawasaki diseaseToxic epidermal necrolysis
Abstract
Severe skin reactions complicating tumor necrosis factor-alpha (TNF-α) antagonist therapy were somewhat reported in adults. We report a case of 24-month-old boy with refractory Kawasaki disease who developed toxic epidermal necrolysis (TEN) after one dose of 5mg/kg infliximab. The patient responded to intravenous hydrocortisone and was able to discharge without any other serious complications. The clinicians should be aware of the potential for severe skin reactions from the use of TNF-α antagonists in children.
Keimyung Author(s)(Kor)
곽아브라함
김성애
최희정
Citation
Abraham Kwak. (2020). Toxic Epidermal Necrolysis Complicating Infliximab Therapy in Refractory Kawasaki Disease. Keimyung Medical Journal, 39(2), 83-85. doi: 10.46308/kmj.2020.00094
Type
Jounral
Source
https://www.e-kmj.org/journal/view.php?doi=10.46308/kmj.2020.00094
DOI
10.46308/kmj.2020.00094
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42813
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2020
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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