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Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea

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Author(s)
Ji Hong YouSang Ah LeeSung-Youn ChunSun Ok SongByung-Wan LeeDae Jung KimEdward J. Boyko
Keimyung Author(s)
You, Ji Hong
Department
Dept. of Internal Medicine (내과학)
Journal Title
Endocrinology and Metabolism
Issued Date
2020
Volume
35
Issue
4
Keyword
COVID-19Diabetes mellitustype 2IncidenceMortalityEpidemiology
Abstract
Background:
The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea.

Methods:
We extracted claims data for patients diagnosed with COVID-19 from the National Health Insurance Service database in Korea from January 20, 2020 to March 31, 2020. We followed up this cohort until death from COVID-19 or discharge from hospital.

Results:
A total of 5,473 patients diagnosed with COVID-19 were analyzed, including 495 with type 2 diabetes and 4,978 without diabetes. Patients with type 2 diabetes were more likely to be treated in the intensive care unit (ICU) (P<0.0001). The incidence of in-hospital mortality was higher in patients with type 2 diabetes (P<0.0001). After adjustment for age, sex, insurance status, and comorbidities, odds of ICU admission (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI], 1.02 to 2.49; P=0.0416) and in-hospital mortality (adjusted OR, 1.90; 95% CI, 1.13 to 3.21; P=0.0161) among patients with COVID-19 infection were significantly higher in those with type 2 diabetes. However, there was no significant difference between patients with and without type 2 diabetes in ventilator, oxygen therapy, antibiotics, antiviral drugs, antipyretics, and the incidence of pneumonia after adjustment.

Conclusion:
COVID-19 positive patients with type 2 diabetes had poorer clinical outcomes with higher risk of ICU admission and in-hospital mortality than those without diabetes. Therefore, medical providers need to consider this more serious clinical course when planning and delivering care to type 2 diabetes patients with COVID-19 infection.
Keimyung Author(s)(Kor)
유지홍
Publisher
School of Medicine (의과대학)
Citation
Ji Hong You et al. (2020). Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea. Endocrinology and Metabolism, 35(4), 901–908. doi: 10.3803/EnM.2020.787
Type
Article
ISSN
2093-5978
Source
https://e-enm.org/journal/view.php?number=2100
DOI
10.3803/EnM.2020.787
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42839
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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