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Correlation between macular edema recurrence and macular capillary network destruction in branch retinal vein occlusion

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Author(s)
Ji Hye JangYu Cheol KimJae Pil Shin
Keimyung Author(s)
Jang, Ji HyeKim, Yu Cheol
Department
Dept. of Ophthalmology (안과학)
Journal Title
BMC ophthalmology
Issued Date
2020
Volume
20
Issue
1
Keyword
Branch retinal vein occlusionMacular capillary networkMacular edemaOptical coherent tomography angiographyVessel density
Abstract
Background:
The aim of this study was to evaluate the correlation between changes in the macular capillary network and macular edema (ME) recurrence with branch retinal vein occlusion (BRVO) using swept-source optical coherence tomography angiography (SS-OCTA).

Methods:
We reviewed the data for 43 patients with treatment-naïve ME associated with BRVO. Patients who received intravitreal bevacizumab injection were divided into two groups based on ME recurrence at 6 months after edema resolution. The perifoveal capillary morphology and the macular capillary vessel density (VD) were retrospectively analyzed using en face SS-OCTA after ME resolution.

Results:
The perifoveal capillary ring loss in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) was more common in the ME recurrence group (n = 22) than in the no ME recurrence group (p = 0.047 and p = 0.002). Relative to the findings in the no ME recurrence groups, the destruction of the perifoveal capillary ring was more severe in the DCP (30.0° vs 87.3°, p = 0.001) than in the SCP (17.3° vs 69.5°, p = 0.006) in the ME recurrence group. The hemi-VD disparity between the affected and the unaffected areas in the SCP and DCP showed significant differences (p = 0.031 and p = 0.017), while macular VD showed no differences between the groups.

Conclusions:
Destruction of the perifoveal capillary ring and hemi-VD disparity could be related to ME recurrence in BRVO. Therefore, these factors may be helpful in predicting ME recurrence.
Keimyung Author(s)(Kor)
장지혜
김유철
Publisher
School of Medicine (의과대학)
Citation
Ji Hye Jang et al. (2020). Correlation between macular edema recurrence and macular capillary network destruction in branch retinal vein occlusion. BMC ophthalmology, 20(1), 341. doi: 10.1186/s12886-020-01611-w
Type
Article
ISSN
1471-2415
Source
https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-020-01611-w
DOI
10.1186/s12886-020-01611-w
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/42978
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
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