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Additional postdilatation using noncompliant balloons after everolimus-eluting stent implantation: Results of the PRESS trial

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Author(s)
Gyung‐Min ParkJae‐Hwan LeeSi Wan ChoiJin‐Ok JeongEun‐Seok ShinJang‐Whan BaeHyuck‐Jun YoonKyung Tae JungJu Yeol BaekWoong Gil ChoiRak Kyeong ChoiSung‐Ho HerJin Bae LeeJon SuhJae Beom LeeSe‐Whan LeeIn‐Ho ChaeSo‐Yeon ChoiIn‐Whan Seong
Keimyung Author(s)
Yoon, Hyuck Jun
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical cardiology
Issued Date
2020
Volume
43
Issue
6
Keyword
drug‐eluting stenteverolimus‐eluting stentnoncompliant balloonpostdilatation
Abstract
Background:
There are limited data on the clinical value of routine postdilatation using noncompliant balloons after contemporary drug‐eluting stent implantation.

Hypothesis:
Additional postdilatation using noncompliant balloons after everolimus‐eluting stent implantation could provide better clinical outcomes.

Methods:
We randomly assigned 1774 patients with coronary artery disease to undergo additional high‐pressure postdilatation using noncompliant balloons and moderate‐pressure dilatation using stent balloons after everolimus‐eluting stent implantation. The primary endpoint was a composite of death, myocardial infarction (MI), stent thrombosis, and target vessel revascularization (TVR) 2 years after randomization.

Results:
The study was discontinued early owing to slow enrollment. In total, 810 patients (406 patients in the high pressure group and 404 in the moderate pressure group) were finally enrolled. At 2 years, the primary endpoint occurred in 3.6% of patients in the high pressure group and in 4.4% of those in the moderate pressure group (P = .537). In addition, no significant differences were observed between the two groups in the occurrence of an individual end point of death (0.8% in the high pressure group vs 1.5% in the moderate group, P = .304), MI (0.2% vs 0.5%, P = .554), stent thrombosis (0% vs 0.2%, P = .316), or TVR (2.8% vs 2.6%, P = .880).

Conclusions:
The strategy of routine postdilatation using noncompliant balloons after everolimus‐eluting stent implantation did not provide incremental clinical benefits.
Keimyung Author(s)(Kor)
윤혁준
Publisher
School of Medicine (의과대학)
Citation
Gyung‐Min Park et al. (2020). Additional postdilatation using noncompliant balloons after everolimus-eluting stent implantation: Results of the PRESS trial. Clinical cardiology, 43(6), 606–613. doi: 10.1002/clc.23355
Type
Article
ISSN
1932-8737
Source
https://onlinelibrary.wiley.com/doi/full/10.1002/clc.23355
DOI
10.1002/clc.23355
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43019
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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