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One-year clinical outcomes of coronary chronic total occlusion intervention in patients with acute coronary syndrome versus stable angina: from the Korean chronic total occlusion registry

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Author(s)
Jah Yeon ChoiByoung Geol ChoiSeung-Woon RhaAhmed MashalyKareem AbdelshafiCheol Ung ChoiCheol Woong YuHyeon-Cheol GwonIn-Ho ChaeHyo-Soo KimHun Sik ParkSeung-Hwan LeeMoo-Hyun KimSeung-Ho HurYangsoo Jang
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Coronary artery disease
Issued Date
2020
Volume
31
Issue
5
Keyword
acute coronary syndromechronic total occlusionpercutaneous coronary interventionstable angina
Abstract
Background:
Chronic total occlusion intervention remains challenging and detailed real-world data on the safety and efficacy of which are limited. This study sought to determine whether there are differences in the 1-year clinical outcomes between chronic total occlusion patients with acute coronary syndrome and stable angina following chronic total occlusion intervention.

Patients and methods:
Data from the Korean chronic total occlusion registry were collected from May 2003 to September 2012, and a total of 3268 patients who underwent chronic total occlusion intervention were enrolled. Cardiovascular outcomes up to 12 months in the acute coronary syndrome group were compared with stable angina group.

Results:
The acute coronary syndrome group consisted of 1657 patients, and stable angina group consisted of 1264 patients. In the acute coronary syndrome group, patients with successful chronic total occlusion intervention had a lower incidence of total death and cardiac death compared to patients with failed intervention. However, there were no significant differences in cardiovascular events in the stable angina group. The successful chronic total occlusion intervention was a significant prognostic factor for lower total death (P = 0.006, hazard ratio = 0.46) and cardiac death (P = 0.003, hazard ratio = 0.36) within acute coronary syndrome group. On the other hand, successful chronic total occlusion intervention was not a prognostic factor for cardiovascular events within stable angina group.

Conclusions:
Successful chronic total occlusion intervention in acute coronary syndrome patients was associated with a lower incidence of cardiovascular outcome compared to patients with failed chronic total occlusion intervention.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine (의과대학)
Citation
Jah Yeon Choi et al. (2020). One-year clinical outcomes of coronary chronic total occlusion intervention in patients with acute coronary syndrome versus stable angina: from the Korean chronic total occlusion registry. Coronary artery disease, 31(5), 430–437. doi: 10.1097/MCA.0000000000000880
Type
Article
ISSN
1473-5830
Source
https://journals.lww.com/coronary-artery/Fulltext/2020/08000/One_year_clinical_outcomes_of_coronary_chronic.5.aspx
DOI
10.1097/MCA.0000000000000880
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43045
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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