계명대학교 의학도서관 Repository

Treatment of epilepsy in adults: Expert opinion in South Korea

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Author(s)
Jung-Ick ByunDong Wook KimKeun Tae KimKwang Ik YangSoon-Tae LeeJong-Geun SeoYoung Joo NoKyung Wook KangDaeyoung KimJae Moon KimYong Won Cho
Keimyung Author(s)
Kim, Keun TaeCho, Yong Won
Department
Dept. of Neurology (신경과학)
Journal Title
Epilepsy & behavior : E&B
Issued Date
2020
Volume
105
Keyword
ConsensusTreatmentGeneralized epilepsyFocal epilepsyAntiepileptic drug
Abstract
Objective:
The aim of this study was to gather the expert opinions of Korean epileptologists regarding the treatment of adult patients with epilepsy.

Methods:
A total of 42 neurologists who specialized in epilepsy were surveyed. They completed an online questionnaire describing multiple patient scenarios. Using these scenarios, they evaluated treatment strategies and gave their preference for specific antiepileptic drugs (AEDs) used to treat genetically mediated generalized epilepsy and focal epilepsy.

Results:
Initial AED monotherapy, followed by a second form of alternative monotherapy or an add-on combination therapy, was the preferred treatment strategy. The experts reached consensus for 87.2% of the items. The most commonly selected AEDs for the initial monotherapy for patients with generalized epilepsy were levetiracetam or valproate. For those with focal epilepsy, levetiracetam, oxcarbazepine, or lamotrigine were the most popular selections. Ethosuximide was the treatment of choice only for patients with generalized epilepsy with prominent absence seizures. Levetiracetam was preferred as an add-on therapy for both generalized and focal epilepsy. For special populations of patients, such as elderly adults or those with comorbid diseases, levetiracetam or lamotrigine was selected as the treatment of choice.

Conclusion:
Most of the survey results were in accordance with the US expert opinion survey published in 2016. This survey can assist clinicians in making clinical decisions when treating individual adult patients with epilepsy.
Keimyung Author(s)(Kor)
김근태
조용원
Publisher
School of Medicine (의과대학)
Citation
Jung-Ick Byun et al. (2020). Treatment of epilepsy in adults: Expert opinion in South Korea. Epilepsy & behavior : E&B, 105, 106942. doi: 10.1016/j.yebeh.2020.106942
Type
Article
ISSN
1525-5069
Source
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1525505019313939
DOI
10.1016/j.yebeh.2020.106942
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43060
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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