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The Frequency of Axial Deposition in Korean Patients With Gout at a Tertiary Spine Center

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Author(s)
Hyo-Joon JinEun-Seok SonDu Hwan Kim
Keimyung Author(s)
Son, Eun Seok
Department
Dept. of Orthopedic Surgery (정형외과학)
Journal Title
Frontiers in Medicine
Issued Date
2020
Volume
7
Keyword
goutspinecomputed tomographytophimonosodium urate deposit
Abstract
Objectives:
This study aimed to describe the frequency of axial deposition (axial gout) and determine the associated factors in patients with gout who presented to a spine clinic in Korea.

Methods:
We enrolled 95 Korean patients who visited our spine center from March 2012 to February 2016 and who had been previously diagnosed with gout and had available computed tomography (CT) images of the vertebral columns. Axial gout was defined as the presence of erosions or tophi in the vertebral endplate or facet joint. The clinical and laboratory data of these patients were retrieved from medical records.

Results:
Out of 95 patients, 15 [15.8%; 95% confidence interval (CI), 9.4-25.0%] had a conventional CT evidence suggestive of axial gout. In these 15 patients, 12 (80%) had lumbar spine involvement (95% CI, 51.4-94.7%). Fifteen patients had erosions of the vertebral column, and two presented with tophi that exhibited erosive changes of the facet joints. The presence of axial gout was not associated with the patients' age, duration of gout, laboratory findings, inflammatory back pain symptoms, identification of monosodium urate crystals in the peripheral joints, current use of urate-lowering drugs, hypertension, and end-stage renal disease; however, there was a significant association with the presence of diabetes (P = 0.008).

Conclusions:
The frequency of axial deposition in Korean patients with gout and spinal symptoms was 15.8%, with the lumbar region being the most commonly involved section of the spine. In addition, diabetes was associated with evidence of axial gout on imaging.
Keimyung Author(s)(Kor)
진효준
손은석
Publisher
School of Medicine (의과대학)
Citation
Hyo-Joon Jin et al. (2020). The Frequency of Axial Deposition in Korean Patients With Gout at a Tertiary Spine Center. Frontiers in Medicine, 7, 339. doi: 10.3389/fmed.2020.00339
Type
Article
ISSN
2296-858X
Source
https://www.frontiersin.org/articles/10.3389/fmed.2020.00339/full
DOI
10.3389/fmed.2020.00339
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43079
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학)
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