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Cardiac CT for Measurement of Right Ventricular Volume and Function in Comparison with Cardiac MRI: A Meta-Analysis

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Author(s)
Jin Young Kim Young Joo Suh Kyunghwa Han Young Jin Kim Byoung Wook Choi
Keimyung Author(s)
Kim, Jin Young
Department
Dept. of Radiology (영상의학)
Journal Title
Korean journal of radiology
Issued Date
2020
Volume
21
Issue
4
Keyword
Right ventricular functionVolumetryComputed tomographyMagnetic resonance imagingMeta-analysis
Abstract
Objective:
We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional parameters.

Materials and methods:
PubMed, EMBASE, and Cochrane library were systematically searched for studies that compared CT with CMRI as the reference standard for measurement of the following RV parameters: end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), or ejection fraction (EF). Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and correlation coefficient (r) between CT and CMRI. Heterogeneity was also assessed. Subgroup analyses were performed based on the probable factors affecting measurement of RV volume: CT contrast protocol, number of CT slices, CT reconstruction interval, CT volumetry, and segmentation methods.

Results:
A total of 766 patients from 20 studies were included. Pooled bias and LOA were 3.1 mL (-5.7 to 11.8 mL), 3.6 mL (-4.0 to 11.2 mL), -0.4 mL (5.7 to 5.0 mL), and -1.8% (-5.7 to 2.2%) for EDV, ESV, SV, and EF, respectively. Pooled correlation coefficients were very strong for the RV parameters (r = 0.87-0.93). Heterogeneity was observed in the studies (I² > 50%, p < 0.1). In the subgroup analysis, an RV-dedicated contrast protocol, ≥ 64 CT slices, CT volumetry with the Simpson's method, and inclusion of the papillary muscle and trabeculation had a lower pooled bias and narrower LOA.

Conclusion:
Cardiac CT accurately measures RV volume and function, with an acceptable range of bias and LOA and strong correlation with CMRI findings. The RV-dedicated CT contrast protocol, ≥ 64 CT slices, and use of the same CT volumetry method as CMRI can improve agreement with CMRI.
Keimyung Author(s)(Kor)
김진영
Publisher
School of Medicine (의과대학)
Citation
Jin Young Kim et al. (2020). Cardiac CT for Measurement of Right Ventricular Volume and Function in Comparison with Cardiac MRI: A Meta-Analysis. Korean journal of radiology, 21(4), 450–461. doi: 10.3348/kjr.2019.0499
Type
Article
ISSN
2005-8330
Source
https://www.kjronline.org/DOIx.php?id=10.3348/kjr.2019.0499
DOI
10.3348/kjr.2019.0499
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43228
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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