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Antiepileptic Drug Therapy for Status Epilepticus

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Author(s)
Daeyoung KimJae-Moon KimYong Won ChoKwang Ik YangDong Wook KimSoon-Tae LeeYoung Joo NoJong-Geun SeoJung-Ick ByunKyung Wook KangKeun Tae Kim
Keimyung Author(s)
Cho, Yong WonKim, Keun Tae
Department
Dept. of Neurology (신경과학)
Journal Title
Journal of Clinical Neurology
Issued Date
2021
Volume
17
Issue
1
Keyword
status epilepticusseizureantiepileptic drugsbenzodiazepinesanestheticsdrug therapy
Abstract
Status epilepticus (SE) is one of the most serious neurologic emergencies. SE is a condition that encompasses a broad range of semiologic subtypes and heterogeneous etiologies. The treatment of SE primarily involves the management of the underlying etiology and the use of antiepileptic drug therapy to rapidly terminate seizure activities. The Drug Committee of the Korean Epilepsy Society performed a review of existing guidelines and literature with the aim of providing practical recommendations for antiepileptic drug therapy. This article is one of a series of review articles by the Drug Committee and it summarizes staged antiepileptic drug therapy for SE. While evidence of good quality supports the use of benzodiazepines as the first-line treatment of SE, such evidence informing the administration of second- or third-line treatments is lacking; hence, the recommendations presented herein concerning the treatment of established and refractory SE are based on case series and expert opinions. The choice of antiepileptic drugs in each stage should consider the characteristics and circumstances of each patient, as well as their estimated benefit and risk to them. In tandem with the antiepileptic drug therapy, careful searching for and treatment of the underlying etiology are required.
Keimyung Author(s)(Kor)
조용원
김근태
Publisher
School of Medicine (의과대학)
Citation
Daeyoung Kim et al. (2021). Antiepileptic Drug Therapy for Status Epilepticus. Journal of Clinical Neurology, 17(1), 11–19. doi: 10.3988/jcn.2021.17.1.11
Type
Article
ISSN
2005-5013
Source
https://www.thejcn.com/search.php?where=aview&id=10.3988/jcn.2021.17.1.11&code=0145JCN&vmode=FULL
DOI
10.3988/jcn.2021.17.1.11
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43348
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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