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Prognostic Factors of COVID-19 Infection in Elderly Patients: A Multicenter Study

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Author(s)
Jihye HwangHo-Sung RyuHyun Ah KimMiri HyunJi Yeon LeeHyon-Ah Yi
Keimyung Author(s)
Hwang, Ji HyeKim, Hyun AhHyun, Mi RiLee, Ji YeonYi, Hyon Ah
Department
Dept. of Neurology (신경과학)
Dept. of Internal Medicine (내과학)
Journal Title
Journal of Clinical Medicine
Issued Date
2020
Volume
9
Issue
12
Keyword
COVID-19SARS-CoV-2novel coronaviruselderlyprognosis
Abstract
The outbreak of the COVID-19 pandemic is a substantial threat to the health of all populations worldwide, and old age is a robust risk factor for poor prognosis of COVID-19 infection. To reduce the fatality rate of COVID-19 infection, further understanding of elderly patients with COVID-19 is necessary. We aimed to investigate the prognostic factors in elderly patients with COVID-19. This was a multicenter and retrospective study. Overall, 340 elderly patients with COVID-19 were enrolled in 3 hospitals in Daegu, South Korea. Death and severe pneumonia requiring oxygen treatment were defined as poor clinical outcomes. Of the patients studied, 15% died and 35.2% were classified as having severe pneumonia. In binary logistic regression analysis, activities of daily living (ADL) impairment, fever during hospitalization, initial infiltration on chest radiograph, and initial increased C-reactive protein (CRP) were significantly associated with severe pneumonia (OR = 5.33, p < 0.001; OR = 3.2, p = 0.002; OR = 2.32, p = 0.044; and OR = 1.33, p < 0.001, respectively). ADL impairment, comorbidity, fever during hospitalization, and initial increased CRP were significantly associated with death (OR = 7.13, p < 0.001; OR = 3.28, p = 0.005; OR = 3.15, p = 0.032, and OR = 1.18, p < 0.001, respectively). ADL impairment, fever, and initial CRP were poor prognostic factors in elderly patients with COVID-19. Understanding these poor prognostic factors is necessary to control the disease in elderly patients.
Keimyung Author(s)(Kor)
황지혜
김현아
현미리
이지연
이현아
Publisher
School of Medicine (의과대학)
Citation
Jihye Hwang et al. (2020). Prognostic Factors of COVID-19 Infection in Elderly Patients: A Multicenter Study. Journal of Clinical Medicine, 9(12), 3932. doi: 10.3390/jcm9123932
Type
Article
ISSN
2077-0383
Source
https://www.mdpi.com/2077-0383/9/12/3932
DOI
10.3390/jcm9123932
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43457
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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