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Clinically Significant Monocyte Biomarker for Differential Diagnosis of COVID-19 Pneumonia in the Emergency Department

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Author(s)
김효원전재천최우익이지연권용식이미진조재완김균무문유호이상훈
Keimyung Author(s)
Jeon, Jae CheonChoi, Woo IkLee, Ji YeonKwon, Yong ShikLee, Sang Hun
Department
Dept. of Emergency Medicine (응급의학)
Dept. of Internal Medicine (내과학)
Journal Title
Keimyung Med J
Issued Date
2021
Volume
40
Issue
1
Keyword
COVID-19EmergenciesMonocytesPneumonia
Abstract
To determine basic patient characteristics and biomarkers to help in the early diagnosis of Coronavirus disease 2019 (COVID-19) pneumonia in patients with pneumonia who visited the emergency department (ED). This retrospective study evaluated patients diagnosed with community-acquired pneumonia (CAP) or COVID-19 pneumonia in the ED at four tertiary medical centers between February 1 and March 31, 2020. Parameters related to the differential diagnosis between CAP and COVID-19 were investigated. Clinical characteristics and laboratory results of biomarkers were analyzed. In total, 81 patients presented to the ED with COVID-19 pneumonia. Multivariate logistic regression analysis showed that monocyte count [odds ratio (OR): 0.996; 95% confidence interval (CI): 0.994–0.999] and pneumonia severity index (PSI) [OR: 1.025; 95% CI: 1.002–1.049] were associated with diagnosis of COVID-19 pneumonia. The area under the curve comprising the combination of monocyte and PSI was 0.789. Differential diagnosis of COVID-19 pneumonia from pneumonia patients who visited the ED can be made by monocyte count and PSI score.
Keimyung Author(s)(Kor)
전재천
최우익
이지연
권용식
이상훈
Citation
김효원. (2021). Clinically Significant Monocyte Biomarker for Differential Diagnosis of COVID-19 Pneumonia in the Emergency Department. Keimyung Med J, 40(1), 26-31. doi: 10.46308/kmj.2021.00024
Type
Journal
Source
https://www.e-kmj.org/journal/view.php?number=2232
DOI
10.46308/kmj.2021.00024
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43539
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2021
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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