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Network Analysis of the Symptoms of Depressive Disorders Over the Course of Therapy: Changes in Centrality Measures

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Author(s)
Seon-Cheol ParkYaeseul KimKiwon KimYoung Sup WooJung-Bum KimEun Young JangHwa-Young LeeHyeon-Woo YimByung-Joo HamJae-Min KimYong Chon Park
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Psychiatry Investig
Issued Date
2021
Volume
18
Issue
1
Keyword
Anxiety (psychic)CentralityDepressive disordersNetwork analysisSymptom-focused approach
Abstract
Objective:
Network analysis can be used in terms of a novel psychopathological approach for depressive syndrome. We aimed to estimate the successive network structures of depressive symptoms in patients with depressive disorder using data from the Clinical Research Center for Depression study.

Methods:
We enrolled 1,152 South Korean adult patients with depressive disorders who were beginning treatment for first-onset or recurrent depressive episodes. We examined the network structure of the severities of the items on the Hamilton Depression Rating Scale (HAMD) at baseline and at weeks 2, 12, 25, and 52. The node strength centrality of all the HAMD items at baseline and at week 2, 12, 25, and 52 in terms of network analysis.

Results:
In the severity networks, the anxiety (psychic) item was the most centrally situated in the initial period (baseline and week 2), while loss of weight was the most centrally situated item in the later period (weeks 25 and 52). In addition, the number of strong edges (i.e., edges representing strong correlations) increased in the late period compared to the initial period.

Conclusion:
Our findings support a period-specific and symptom-focused therapeutic approach that can provide complementary information to the unidimensional total HAMD score.
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine (의과대학)
Citation
Seon-Cheol Park et al. (2021). Network Analysis of the Symptoms of Depressive Disorders Over the Course of Therapy: Changes in Centrality Measures. Psychiatry Investig, 18(1), 48–58. doi: 10.30773/pi.2020.0367
Type
Article
ISSN
1976-3026
Source
https://www.psychiatryinvestigation.org/journal/view.php?doi=10.30773/pi.2020.0367
DOI
10.30773/pi.2020.0367
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43653
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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