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Optimized Criteria for Sentinel Lymph Node Biopsy in Patients with Clinically Node Negative Breast Cancer

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Author(s)
Jeong Suk KimMoo Hyun LeeSun Hee KangJihyoung Cho
Keimyung Author(s)
Lee, Moo HyunKang, Sun HeeCho, Ji Hyoung
Department
Dept. of Surgery (외과학)
Journal Title
J Breast Dis
Issued Date
2021
Volume
9
Issue
1
Keyword
Breast neoplasmsLymph node excisionSentinel lymph node biopsy
Abstract
Purpose:
Sentinel lymph node biopsy (SLNB) is a well-established staging procedure for patients with early breast cancer who have clinically negative axillary lymph node. However, no consensus exists about the number of sentinel lymph nodes (SLN) that should be removed based on radioactivity counts in breast cancer. We reviewed and analyzed cases in which more than one SLN was detected and there was at least one pathologically positive node.

Methods:
We retrospectively studied breast cancer patients who underwent lymphoscintigraphy with injection of a radioactive colloid and SLNB along with intraoperative determination of radioactive counts of lymph nodes using a gamma probe between 2006 and 2018. In total 326 patients with more than one radioactive SLN were enrolled in this study.

Results:
Fifty-four patients had nodal metastases, of whom 46 (85.2%) had metastases in the hottest lymph node. All metastatic SLNs were identified as one of the first three lymph nodes dissected. The lowest radioactive count of a positive SLN corresponded to 10% of that of the hottest node.

Conclusion:
We suggest that removal of the first three lymph nodes or nodes covered by the "10% rule" is sufficient in SLNB for patients with breast cancer.
Keimyung Author(s)(Kor)
이무현
강선희
조지형
Publisher
School of Medicine (의과대학)
Citation
Jeong Suk Kim et al. (2021). Optimized Criteria for Sentinel Lymph Node Biopsy in Patients with Clinically Node Negative Breast Cancer. J Breast Dis, 9(1), 26–29. doi: 10.14449/jbd.2021.9.1.26
Type
Article
ISSN
2288-5560
Source
https://www.jbd.or.kr/journal/view.php?number=130
DOI
10.14449/jbd.2021.9.1.26
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43676
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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