계명대학교 의학도서관 Repository

Reliability of Coronary Artery Calcium Severity Assessment on Non-Electrocardiogram-Gated CT: A Meta-Analysis

Metadata Downloads
Author(s)
Jin Young KimYoung Joo SuhKyunghwa HanByoung Wook Choi
Keimyung Author(s)
Kim, Jin Young
Department
Dept. of Radiology (영상의학)
Journal Title
Korean J Radiol
Issued Date
2021
Volume
22
Issue
7
Keyword
Coronary artery calciumComputed tomographyReliabilityMeta-analysis
Abstract
Objective:
The purpose of this meta-analysis was to investigate the pooled agreements of the coronary artery calcium (CAC) severities assessed by electrocardiogram (ECG)-gated and non-ECG-gated CT and evaluate the impact of the scan parameters.

Materials and Methods:
PubMed, EMBASE, and the Cochrane library were systematically searched. A modified Quality Assessment of Diagnostic Accuracy Studies-2 tool was used to evaluate the quality of the studies. Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and the correlation coefficient of the CAC scores or the weighted kappa for the categorization of the CAC severities detected by the two modalities. The heterogeneity among the studies was also assessed. Subgroup analyses were performed based on factors that could affect the measurement of the CAC score and severity: slice thickness, reconstruction kernel, and radiation dose for non-ECG-gated CT.

Results:
A total of 4000 patients from 16 studies were included. The pooled bias was 62.60, 95% LOA were −36.19 to 161.40, and the pooled correlation coefficient was 0.94 (95% confidence interval [CI] = 0.89–0.97) for the CAC score. The pooled weighted kappa of the CAC severity was 0.85 (95% CI = 0.79–0.91). Heterogeneity was observed in the studies (I2 > 50%, p < 0.1). In the subgroup analysis, the agreement between the CAC categorizations was better when the two CT examinations had reconstructions based on the same slice thickness and kernel.

Conclusion:
The pooled agreement of the CAC severities assessed by the ECG-gated and non-ECG-gated CT was excellent; however, it was significantly affected by scan parameters, such as slice thickness and the reconstruction kernel.
Keimyung Author(s)(Kor)
김진영
Publisher
School of Medicine (의과대학)
Citation
Jin Young Kim et al. (2021). Reliability of Coronary Artery Calcium Severity Assessment on Non-Electrocardiogram-Gated CT: A Meta-Analysis. Korean J Radiol, 22(7), 1034–1043. doi: 10.3348/kjr.2020.1047
Type
Article
ISSN
2005-8330
Source
https://www.kjronline.org/search.php?where=aview&id=10.3348/kjr.2020.1047&code=0068KJR&vmode=FULL
DOI
10.3348/kjr.2020.1047
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43687
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.