계명대학교 의학도서관 Repository

Characteristics, Location, and Clinical Outcomes of Gastrointestinal Bleeding in Patients Taking New Oral Anticoagulants Compared to Vitamin K Antagonists

Metadata Downloads
Author(s)
A Reum ChoeChang Mo MoonChung Hyun TaeJaeyoung ChunKi Bae BangYoo Jin LeeHyun Seok LeeYunho JungSung Chul ParkHoon Sup Koo
Keimyung Author(s)
Lee, Yoo Jin
Department
Dept. of Internal Medicine (내과학)
Journal Title
J Clin Med
Issued Date
2021
Volume
10
Issue
12
Keyword
gastrointestinal bleedingnew oral anticoagulantsvitamin K antagonistrebleeding
Abstract
New oral anticoagulants (NOACs) are commonly used in clinical practice as alternatives to vitamin K antagonists (VKA). However, the etiology, clinical course, and risk of gastrointestinal (GI) bleeding remain unclear. We aimed to evaluate the clinical characteristics and location of acute GI bleeding associated with NOACs and its severity and outcomes compared to VKA. This retrospective multicenter study included 381 subjects on anticoagulants who underwent appropriate diagnostic examination due to GI bleeding. Regarding the characteristics of acute GI bleeding, the proportion of vascular lesions was significantly lower in the NOACs group than that in the VKA group. Small bowel bleeding occurred less commonly in the NOACs group, but the difference did not reach statistical significance. Regarding severity and clinical outcomes, patients on NOACs received significantly smaller volumes of transfused blood products and had shorter ICU stays than those on VKA. Moreover, the need for surgery and the risk of rebleeding in the NOACs group were significantly lower than those in the VKA group. Patients on NOACs have better clinical outcomes in terms of severity of acute GI bleeding or rebleeding than patients on VKA. Patients on NOACs demonstrate different characteristics and location of acute GI bleeding than those on VKA.
Keimyung Author(s)(Kor)
이유진
Publisher
School of Medicine (의과대학)
Citation
A Reum Choe et al. (2021). Characteristics, Location, and Clinical Outcomes of Gastrointestinal Bleeding in Patients Taking New Oral Anticoagulants Compared to Vitamin K Antagonists. J Clin Med, 10(12), 2693. doi: 10.3390/jcm10122693
Type
Article
ISSN
2077-0383
Source
https://www.mdpi.com/2077-0383/10/12/2693
DOI
10.3390/jcm10122693
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43813
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.