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Natural History of Isolated Below-Knee Vein Thrombosis in Patients with Spinal Cord Injury

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Author(s)
Jang-Hyuk ChoDong-Gyu Lee
Keimyung Author(s)
Cho, Jang Hyuk
Department
Dept. of Rehabilitation Medicine (재활의학)
Journal Title
Healthcare (Basel)
Issued Date
2021
Volume
9
Issue
7
Keyword
spinal cord injurydeep vein thrombosisanticoagulationdistal deep vein thrombosissurveillance
Abstract
In the general population, serial imaging is recommended over anticoagulant therapy for below-knee deep vein thrombosis (BKDVT). However, no clinical trial in Asian patients with spinal cord injury and BKDVT has been performed. Therefore, we evaluated the natural course of BKDVT in patients with acute spinal cord injury. We retrospectively analyzed inpatients with spinal cord injury with BKDVT between 2016 and 2020. All patients underwent inpatient rehabilitation treatment and duplex ultrasonographic examination of both the lower extremities at follow-up. After screening 172 patients with acute spinal cord injury for deep vein thrombosis using duplex ultrasound, 27 patients with below-the-knee deep vein thrombosis were included in this study. The mean lower-extremity motor score (median, interquartile range) was 66.0, 54.0–74.5. Sixteen patients received a non-vitamin K antagonist oral anticoagulant (NOAC) for anticoagulation. None of the patients had proximal propagation according to the follow-up duplex ultrasonography. BKDVT disappearance was not significantly different between the NOAC treatment and non-treatment groups. Asian patients with spinal cord injury have a low incidence of venous thromboembolism and favorable natural history of BKDVT. We recommend serial imaging over anticoagulant therapy for BKDVT in these patients.
Keimyung Author(s)(Kor)
조장혁
Publisher
School of Medicine (의과대학)
Citation
Jang-Hyuk Cho and Dong-Gyu Lee. (2021). Natural History of Isolated Below-Knee Vein Thrombosis in Patients with Spinal Cord Injury. Healthcare (Basel), 9(7), 861. doi: 10.3390/healthcare9070861
Type
Article
ISSN
2227-9032
Source
https://www.mdpi.com/2227-9032/9/7/861
DOI
10.3390/healthcare9070861
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43944
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학)
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