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Differential Factors for Predicting Outcomes in Left Main versus Non-Left Main Coronary Bifurcation Stenting

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Author(s)
Jung-Joon ChaSoon Jun HongHyung Joon JooJae Hyoung ParkCheol Woong YuTae Hoon AhnHyo-Soo KimWoo Jung ChunSeung-Ho HurSeung Hwan HanSeung-Woon RhaIn-Ho ChaeJin-Ok JeongJung Ho HeoJunghan YoonKi Hong ChoiYoung Bin SongHyeon-Cheol GwonJong-Seon ParkMyeong-Ki HongJoon-Hyung DohKwang Soo ChaDoo-Il KimSang Yeub LeeKiyuk ChangByung-Hee HwangSo-Yeon ChoiMyung Ho JeongChang-Wook NamBon-Kwon Koo andDo-Sun Lim
Keimyung Author(s)
Hur, Seung HoNam, Chang Wook
Department
Dept. of Internal Medicine (내과학)
Journal Title
J Clin Med
Issued Date
2021
Volume
10
Issue
14
Keyword
coronary bifurcation stentingpredictorclinical outcomedrug-eluting stents
Abstract
Background:
No large-scale study has compared the clinical and angiographic predictors of cardiovascular events in patients with left main bifurcation (LMB) and non-LMB stenting after second-generation DES implantation. Herein, we investigated differential clinical and angiographic factors for predicting outcomes in LMB versus non-LMB stenting.

Methods:
A total of 2648 patients with bifurcation lesions treated with second-generation DESs from the retrospective patient cohort were divided into an LMB group (n = 935) and a non-LMB group (n = 1713). The primary outcome was the 7-year incidence of target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, and target lesion revascularization.

Results:
The incidence of TLF was 9.8%. Those in the LMB group were associated with a higher risk of TLF (14.2% versus 7.5%, p < 0.001) than those in the non-LMB group. Regarding the LMB group, independent predictors of TLF were chronic kidney disease (CKD), reduced left ventricular ejection fraction (LVEF), and two-stenting. Regarding the non-LMB group, CKD, reduced LVEF, old age, diabetes, and small diameter of the main vessel stent were independent predictors of TLF.

Conclusions:
The two-stent strategy could potentially increase TLF for the LMB lesions, and achieving the maximal diameter of the main vessel stent could result in better clinical outcomes for non-LMB lesions.
Keimyung Author(s)(Kor)
허승호
남창욱
Publisher
School of Medicine (의과대학)
Citation
Jung-Joon Cha et al. (2021). Differential Factors for Predicting Outcomes in Left Main versus Non-Left Main Coronary Bifurcation Stenting. J Clin Med, 10(14), 3024. doi: 10.3390/jcm10143024
Type
Article
ISSN
2077-0383
Source
https://www.mdpi.com/2077-0383/10/14/3024
DOI
10.3390/jcm10143024
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/43962
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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