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Treatment Pattern of Antithrombotic Therapy over Time after Percutaneous Coronary Intervention in Patients with Atrial Fibrillation in Real-World Practice in Korea

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Author(s)
Seongwook HanSola HanSung-Won JangMyung-Yong LeeYoung-Keun OnOh Young BangJi-Min LeeYoo-Jung ParkJi-Soo ShinSeongsik KangHae Sun SuhYoung-Hoon Kim
Keimyung Author(s)
Han, Seong Wook
Department
Dept. of Internal Medicine (내과학)
Journal Title
Healthcare (Basel)
Issued Date
2021
Volume
9
Issue
9
Abstract
We examined antithrombotic treatment patterns with clinical characteristics and therapy changes over time in patients with atrial fibrillation (AF) after percutaneous coronary intervention (PCI). Using the Health Insurance Review and Assessment service claims database (01JAN2007-30NOV2016) in Korea, we included adult patients with AF and PCI: (1) who underwent PCI with stenting between 01JAN2008 and 30NOV2016; (2) with ≥1 claim for AF (ICD code: I48) (3) with antithrombotics 1 day prior to or at the date of PCI; and (4) with CHADS2-VASc of ≥2. In this study, 7749 patients with AF who underwent PCI, triple therapy, dual therapy, dual antiplatelet therapy (DAPT), and single antiplatelet therapy were prescribed to 24.6%, 3.4%, 60.8%, and 11.0%, respectively. In the triple therapy group, 23.1% persisted with triple therapy for 12 months, whereas the remaining patients switched to a different therapy. In the entire cohort and several subgroups, the median treatment duration of triple therapy was 55–87 days. DAPT use for 12 months was the most common treatment pattern (62.6%) in the DAPT group (median treatment duration, 324–345 days). A significant discrepancy exists between the current guidelines and real-world practice regarding antithrombotic treatment with PCI for patients with AF. Appropriate use of anticoagulants should be emphasized.
Keimyung Author(s)(Kor)
한성욱
Publisher
School of Medicine (의과대학)
Citation
Seongwook Han et al. (2021). Treatment Pattern of Antithrombotic Therapy over Time after Percutaneous Coronary Intervention in Patients with Atrial Fibrillation in Real-World Practice in Korea. Healthcare (Basel), 9(9), 1185. doi: 10.3390/healthcare9091185
Type
Article
ISSN
2227-9032
Source
https://www.mdpi.com/2227-9032/9/9/1185
DOI
10.3390/healthcare9091185
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44029
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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