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Evaluation of the Ostium in Anomalous Origin of the Right Coronary Artery with an Interarterial Course Using Dynamic Cardiac CT and Implications of Ostial Findings

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Author(s)
Jin-Young KimYoo Jin HongKyunghwa HanSuji LeeYoung Jin KimByoung Wook ChoiHye-Jeong Lee
Keimyung Author(s)
Kim, Jin Young
Department
Dept. of Radiology (영상의학)
Journal Title
Korean J Radiol
Issued Date
2022
Volume
23
Issue
2
Keyword
Coronary vessel anomalyCoronary computed tomography angiographyCardiac computed tomographyRetrospective gating
Abstract
Objective:
We aimed to evaluate the ostium of right coronary artery of anomalous origin from the left coronary sinus (AORL) with an interarterial course throughout the cardiac cycle on CT and analyze the clinical significance of the ostial findings.

Materials and Methods:
From January 2011 to December 2015, 68 patients (41 male, 57.3 ± 12.1 years) with AORL with an interarterial course and retrospective cardiac CT data were included. AORL was classified as high or low ostial location based on the pulmonary annulus in the diastolic and systolic phases on cardiac CT. In addition, the height, width, height/width ratio, area, and angle of the ostium were measured in both cardiac phases. After cardiac CT, patients were followed until December 31, 2020 for major adverse cardiac events (MACE). Clinical and CT characteristics associated with MACE were explored using Cox regression analysis.

Results:
During a median follow-up period of 2071 days (interquartile range, 1180.5–2747.3 days), 13 patients experienced MACE (19.1%, 13/68). Seven (10.3%, 7/68) had the ostial location change from high in the diastolic phase to low in the systolic phase. In the univariable analysis, younger age (hazard ratio [HR] = 0.918, p < 0.001), high ostial location (HR = 4.008, p = 0.036), larger height/width ratio (HR = 5.621, p = 0.049), and smaller ostial angle (HR = 0.846, p = 0.048) in the systolic phase were significant predictors of MACE. In multivariable cox regression analysis, younger age (adjusted HR = 0.917, p = 0.002) and high ostial location in the systolic phase (adjusted HR = 4.345, p = 0.026) were independent predictors of MACE.

Conclusion:
The ostial location of AORL with an interarterial course can change during the cardiac cycle, and high ostial location in the systolic phase was an independent predictor of MACE.
Keimyung Author(s)(Kor)
김진영
Publisher
School of Medicine (의과대학)
Citation
Jin-Young Kim et al. (2022). Evaluation of the Ostium in Anomalous Origin of the Right Coronary Artery with an Interarterial Course Using Dynamic Cardiac CT and Implications of Ostial Findings. Korean J Radiol, 23(2), 172–179. doi: 10.3348/kjr.2021.0270
Type
Article
ISSN
2005-8330
Source
https://www.kjronline.org/DOIx.php?id=10.3348/kjr.2021.0270
DOI
10.3348/kjr.2021.0270
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44090
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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