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Mortality prognostic factors of COVID-19 in the emergency department during outbreak in Daegu, Korea: a multicenter retrospective study

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Author(s)
Jong-yeon KimJung Ho KimHyun Wook RyooJae Yun AhnSungbae MoonDong Eun LeeSang Hun LeeYou Ho MunTae Chang Jang
Keimyung Author(s)
Lee, Sang Hun
Department
Dept. of Emergency Medicine (응급의학)
Journal Title
J Korean Soc Emerg Med
Issued Date
2022
Volume
33
Issue
1
Keyword
CoronavirusDisease outbreaksEmergency treatmentPrognosisMortality
Abstract
Objective:
We aimed to investigate the characteristics and prognostic factors of coronavirus disease 2019 (COVID-19) patients in the emergency departments (EDs) in Daegu, Korea, the region with the second regional outbreak worldwide.

Method:
We conducted a retrospective observational multicenter study using a population-based COVID-19 registry of EDs. We included the demographic, clinical and laboratory data. Cox proportional hazard regression analysis was performed to identify the prognostic factors of mortality.

Results:
A total of 241 patients were included in this study. In the Cox hazard regression model (hazard ratio [95% confidence interval]), age (65-79 years: 3.531 [1.529-8.156], ≥80 years: 5.335 [2.229-12.770]), respiratory rate (RR) (>20 breaths/min: 2.025 [1.205-3.403], ≤11 breaths/min: 111.292 [30.845-401.555]), lymphocyte counts <1.0×109/L (2.611 [1.494-4.739]), blood urea nitrogen (BUN) levels>23 mg/dL (2.047 [1.233-3.399]), aspartate aminotransferase (AST) levels>40 IU/L (1.785 [1.009-3.158]) and neutrophil counts>6.3×109/L (1.638 [1.014-2.644]) were associated with mortality.

Conclusion:
Age, RR, lymphocyte counts, BUN levels, AST levels and neutrophil counts were prognostic factors in COVID-19 patients in the ED. These factors can help effectively treat and reduce mortality through optimized management of COVID-19 patients, in places with limited emergency medical resources such as massive regional outbreaks.
Keimyung Author(s)(Kor)
이상훈
Publisher
School of Medicine (의과대학)
Citation
Jong-yeon Kim et al. (2022). Mortality prognostic factors of COVID-19 in the emergency department during outbreak in Daegu, Korea: a multicenter retrospective study. J Korean Soc Emerg Med, 33(1), 94–105.
Type
Article
ISSN
2384-048X
Source
https://www.jksem.org/journal/view.php?year=2022&vol=33&spage=94
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44099
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
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