계명대학교 의학도서관 Repository

Clinical impact of guideline-based practice and patients' adherence in uncontrolled hypertension

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Author(s)
Il Suk SohnChong Jin KimByung-Su YooByung Jin KimJae Woong ChoiDoo-Il KimSang-Hak LeeWoo-Hyuk SongDong Woon JeonTae Jun ChaDae-Kyeong KimSeong-Hoon LimChang-Wook NamJoon-Han ShinUng KimJae-Jin KwakJun-Bean ParkJin-Hye ChaYoung-Joo KimJimi ChoiJuneyoung Lee
Keimyung Author(s)
Nam, Chang Wook
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clin Hypertens
Issued Date
2021
Volume
27
Issue
1
Keyword
Treatment adherence and complianceQuality of lifePatient satisfaction
Abstract
Background:
Chronic diseases like hypertension need comprehensive lifetime management. This study assessed clinical and patient-reported outcomes and compared them by treatment patterns and adherence at 6 months among uncontrolled hypertensive patients in Korea.

Methods:
This prospective, observational study was conducted at 16 major hospitals where uncontrolled hypertensive patients receiving anti-hypertension medications (systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg) were enrolled during 2015 to 2016 and studied for the following 6 months. A review of medical records was performed to collect data on treatment patterns to determine the presence of guideline-based practice (GBP). GBP was defined as: (1) maximize first medication before adding second or (2) add second medication before reaching maximum dose of first medication. Patient self-administered questionnaires were utilized to examine medication adherence, treatment satisfaction and quality of life (QoL).

Results:
A total of 600 patients were included in the study. Overall, 23% of patients were treated based on GBP at 3 months, and the GBP rate increased to 61.4% at 6 months. At baseline and 6 months, 36.7 and 49.2% of patients, respectively, were medication adherent. The proportion of blood pressure-controlled patients reached 65.5% at 6 months. A higher blood pressure control rate was present in patients who were on GBP and also showed adherence than those on GBP, but not adherent, or non-GBP patients (76.8% vs. 70.9% vs. 54.2%, P < 0.001). The same outcomes were found for treatment satisfaction and QoL (P < 0.05).

Conclusions:
This study demonstrated the importance of physicians' compliance with GBP and patients' adherence to hypertensive medications. GBP compliance and medication adherence should be taken into account when setting therapeutic strategies for better outcomes in uncontrolled hypertensive patients.
Keimyung Author(s)(Kor)
남창욱
Publisher
School of Medicine (의과대학)
Citation
Il Suk Sohn et al. (2021). Clinical impact of guideline-based practice and patients’ adherence in uncontrolled hypertension. Clin Hypertens, 27(1), 26. doi: 10.1186/s40885-021-00183-1
Type
Article
ISSN
2056-5909
Source
https://clinicalhypertension.biomedcentral.com/articles/10.1186/s40885-021-00183-1
DOI
10.1186/s40885-021-00183-1
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44110
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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