계명대학교 의학도서관 Repository

Therapeutic effect of steroids on vestibular neuritis: Systematic review and meta-analysis

Metadata Downloads
Author(s)
Gaeun KimJae-Hyun SeoSeung Jae LeeDong-Hee Lee
Keimyung Author(s)
Kim, Ga Eun
Department
Dept. of Nursing (간호학)
Journal Title
Clin Otolaryngol
Issued Date
2022
Volume
47
Issue
1
Keyword
caloric testsmeta-analysisrecovery of functionsteroidsvestibular neuritis
Abstract
Objectives:
The present meta-analysis sought to assess further evidence for the efficacy of steroids in vestibular neuritis (VN).

Methods:
The PubMed, EMBASE and Cochrane Library databases were searched through 30 August 2019. The main outcome measure was dizziness handicap inventory (DHI) and secondary outcomes included complete caloric recovery and improvement of canal paresis (CP). The follow-up times were divided into short, mid and long-term.

Results:
Among 276 records identified, 5 studies (n = 253) were included in the analysis. The therapeutic effect of steroid on VN was confirmed (Hedges' g = 0.172, 95% CI 0.05–0.30, p = .006). Although there was no significant difference between steroids and control in the DHI score (Hedges' g = −0.323, 95% CI −0.533 to −0.113, p < .01), significant effect was seen on complete caloric recovery and improvement in CP (Hedges' g = 0.364, 95% CI 0.18–0.55, p < .0001; Hedges' g = 0.592, 95% CI 0.32–0.59, p < .0001).

Conclusions:
The results suggest that corticosteroids have an effect on the results of caloric tests for VN recovery, especially in long-term follow-up. However, in terms of dizziness handicap, we did not find any evidence of positive effect on corticosteroid. More data are required before recommendations can be made regarding management in patients on corticosteroids.
Keimyung Author(s)(Kor)
김가은
Publisher
College of Nursing (간호대학)
Citation
Gaeun Kim et al. (2022). Therapeutic effect of steroids on vestibular neuritis: Systematic review and meta-analysis. Clin Otolaryngol, 47(1), 34–43. doi: 10.1111/coa.13880
Type
Article
ISSN
1749-4486
Source
https://onlinelibrary.wiley.com/doi/10.1111/coa.13880
DOI
10.1111/coa.13880
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44111
Appears in Collections:
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록
  • 관련 파일이 존재하지 않습니다.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.