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Leg paralysis after AstraZeneca COVID-19 vaccination diagnosed as neuralgic amyotrophy of the lumbosacral plexus: a case report

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Author(s)
Se Il KimHung Youl SeokJaehyuck YiJang Hyuk Cho
Keimyung Author(s)
Seok, Hung YoulYi, Jae HyuckCho, Jang Hyuk
Department
Dept. of Neurology (신경과학)
Dept. of Radiology (영상의학)
Dept. of Rehabilitation Medicine (재활의학)
Journal Title
J Int Med Res
Issued Date
2021
Volume
49
Issue
11
Keyword
Coronavirus disease 2019vaccinationlumbosacral plexusparalysiscase reportcomplication
Abstract
The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Based on the clinical, electrodiagnostic, and radiologic findings, the patient was diagnosed with post-vaccination NA. We speculate that the COVID-19 vaccine elicited an immune-mediated inflammatory response to the injected antigen due to inflammatory immunity in a patient with predisposed susceptibility to NA.
Keimyung Author(s)(Kor)
석흥열
이재혁
조장혁
Publisher
School of Medicine (의과대학)
Citation
Se Il Kim et al. (2021). Leg paralysis after AstraZeneca COVID-19 vaccination diagnosed as neuralgic amyotrophy of the lumbosacral plexus: a case report. J Int Med Res, 49(11), 1–5. doi: 10.1177/03000605211056783
Type
Article
ISSN
1473-2300
Source
https://journals.sagepub.com/doi/10.1177/03000605211056783
DOI
10.1177/03000605211056783
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44131
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
1. School of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학)
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