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Effects and safety of COVID-19 vaccination on assisted reproductive technology and pregnancy: A comprehensive review and joint statements of the KSRM, the KSRI, and the KOSAR

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Author(s)
Ae Ra HanDayong LeeSeul Ki KimChang Woo ChooJoon Cheol ParkJung Ryeol LeeWon Jun ChoiJin Hyun JunJeong Ho RheeSeok Hyun Kim
Keimyung Author(s)
Park, Joon CheolRhee, Jeong Ho
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Clin Exp Reprod Med
Issued Date
2022
Volume
49
Issue
1
Keyword
Assisted reproductive technologyCOVID-19LactationPregnancyVaccination
Abstract
Humanity is in the midst of the coronavirus disease 2019 (COVID-19) pandemic, and vaccines—including mRNA vaccines—have been developed at an unprecedented speed. It is necessary to develop guidelines for vaccination for people undergoing treatment with assisted reproductive technology (ART) and for pregnancy-related situations based on the extant laboratory and clinical data. COVID-19 vaccines do not appear to adversely affect gametes, embryos, or implantation; therefore, active vaccination is recommended for women or men who are preparing for ART. The use of intravenous immunoglobulin G (IVIG) for the treatment of immune-related infertility is unlikely to impact the effectiveness of the vaccines, so COVID-19 vaccines can be administered around ART cycles in which IVIG is scheduled. Pregnant women have been proven to be at risk of severe maternal and neonatal complications from COVID-19. It does not appear that COVID-19 vaccines harm pregnant women or fetuses; instead, they have been observed to deliver antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the fetus. Accordingly, it is recommended that pregnant women receive COVID-19 vaccination. There is no rationale for adverse effects, or clinical cases of adverse reactions, in mothers or neonates after COVID-19 vaccination in lactating women. Instead, antibodies to SARS-CoV-2 can be delivered through breast milk. Therefore, breastfeeding mothers should consider vaccination. In summary, active administration of COVID-19 vaccines will help ensure the safe implementation of ART, pregnancy, and breastfeeding.
Keimyung Author(s)(Kor)
박준철
이정호
Publisher
School of Medicine (의과대학)
Citation
Ae Ra Han et al. (2022). Effects and safety of COVID-19 vaccination on assisted reproductive technology and pregnancy: A comprehensive review and joint statements of the KSRM, the KSRI, and the KOSAR. Clin Exp Reprod Med, 49(1), 2–8. doi: 10.5653/cerm.2022.05225
Type
Article
ISSN
2233-8241
Source
https://ecerm.org/journal/view.php?doi=10.5653/cerm.2022.05225
DOI
10.5653/cerm.2022.05225
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44179
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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