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Association between CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients

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Author(s)
Hyung Jun KimMoo-Seok ParkJoonsang YooYoung Dae KimHyungjong ParkByung Moon KimOh Young BangHyeon Chang KimEuna HanDong Joon KimJoonNyung HeoJin Kyo ChoiKyung-Yul LeeHye Sun LeeDong Hoon ShinHye-Yeon ChoiSung-Il SohnJeong-Ho HongJong Yun LeeJang-Hyun BaekGyu Sik KimWoo-Keun SeoJong-Won ChungSeo Hyun KimSang Won HanJoong Hyun ParkJinkwon KimYo Han JungHan-Jin ChoSeong Hwan AhnSung Ik LeeKwon-Duk SeoYoonkyung ChangTae-Jin SongHyo Suk Nam
Keimyung Author(s)
Park, Hyung JongSohn, Sung IlHong, Jeong Ho
Department
Dept. of Neurology (신경과학)
Journal Title
J Clin Med
Issued Date
2022
Volume
11
Issue
1
Keyword
ischemic strokestroke risk scorerecanalizationthrombectomy
Abstract
Background: The CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198–2.009, p = 0.001; CHA2DS2VASc score: OR 1.269, 95% CI 1.080–1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011–1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167–1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554–0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.
Keimyung Author(s)(Kor)
박형종
손성일
홍정호
Publisher
School of Medicine (의과대학)
Citation
Hyung Jun Kim et al. (2022). Association between CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients. J Clin Med, 11(1), 274. doi: 10.3390/jcm11010274
Type
Article
ISSN
2077-0383
Source
https://www.mdpi.com/2077-0383/11/1/274
DOI
10.3390/jcm11010274
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44192
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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