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Early experience of laparoscopic resection and comparison with open surgery for gastric gastrointestinal stromal tumor: a multicenter retrospective study

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Author(s)
Shin-Hoo ParkHyuk-Joon LeeMin-Chan KimJeong-Hwan YookTae-Sung SohnWoo-Jin HyungSeung-Wan RyuYukinori KurokawaYoung-Woo KimSang-Uk HanHyung-Ho KimDo-Joong ParkWook KimSang-Il LeeHaruhiko ChoGyu-Seok ChoJin-Jo KimKi-Han KimMoon-Won YooHan-Kwang Yang
Keimyung Author(s)
Ryu, Seung Wan
Department
Dept. of Surgery (외과학)
Journal Title
Sci Rep
Issued Date
2022
Volume
12
Issue
1
Abstract
The advantages of laparoscopic resection over open surgery in the treatment of gastric gastrointestinal stromal tumor (GIST) are not conclusive. This study aimed to evaluate the postoperative and oncologic outcome of laparoscopic resection for gastric GIST, compared to open surgery. We retrospectively reviewed the prospectively collected database of 1019 patients with gastric GIST after surgical resection at 13 Korean and 2 Japanese institutions. The surgical and oncologic outcomes were compared between laparoscopic and open group, through 1:1 propensity score matching (PSM). The laparoscopic group (N = 318) had a lower rate of overall complications (3.5% vs. 7.9%, P = 0.024) and wound complications (0.6% vs. 3.1%, P = 0.037), shorter hospitalization days (6.68 ± 4.99 vs. 8.79 ± 6.50, P < 0.001) than the open group (N = 318). The superiority of the laparoscopic approach was also demonstrated in patients with tumors larger than 5 cm, and at unfavorable locations. The recurrence-free survival was not different between the two groups, regardless of tumor size, locational favorableness, and risk classifications. Cox regression analysis revealed that tumor size larger than 5 cm, higher mitotic count, R1 resection, and tumor rupture during surgery were independent risk factors for recurrence. Laparoscopic surgery provides lower rates of complications and shorter hospitalizations for patients with gastric GIST than open surgery.
Keimyung Author(s)(Kor)
류승완
Publisher
School of Medicine (의과대학)
Citation
Shin-Hoo Park et al. (2022). Early experience of laparoscopic resection and comparison with open surgery for gastric gastrointestinal stromal tumor: a multicenter retrospective study. Sci Rep, 12(1), 2290. doi: 10.1038/s41598-022-05044-x
Type
Article
ISSN
2045-2322
Source
https://www.nature.com/articles/s41598-022-05044-x
DOI
10.1038/s41598-022-05044-x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44218
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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