계명대학교 의학도서관 Repository

Central retinal thickness changes and risk of neovascular glaucoma after intravitreal bevacizumab injection in patients with central retinal vein occlusion

Metadata Downloads
Author(s)
You Hyun LeeYu Cheol Kim
Keimyung Author(s)
Lee, You HyunKim, Yu Cheol
Department
Dept. of Ophthalmology (안과학)
Journal Title
Sci Rep
Issued Date
2022
Volume
12
Issue
1
Abstract
This retrospective study evaluated changes in the central retinal thickness (CRT) and the risk factors for neovascular glaucoma (NVG) after intravitreal bevacizumab injection under a pro re nata (PRN) regimen for macular oedema in 57 eyes with central retinal vein occlusion (CRVO). The clinical characteristics at the time of NVG diagnosis were assessed, and baseline and final clinical characteristics and mean CRT values at 1-, 3-, and 6-month follow-up evaluations were recorded. The incidence of NVG was 21.1%, with the neovascular group (12 eyes) showing poor baseline and final visual acuity, a higher incidence of baseline ischaemic-type CRVO and subretinal fluid, a higher mean CRT at the 1-month follow-up, and a higher number of intravitreal bevacizumab injections during the 6-month follow-up. Nine eyes with NVG (75%) showed a mean CRT < 300 μm at the time of diagnosis. An ischaemic CRVO and higher CRT at the 1-month follow-up were related to the development of NVG in the multivariate analysis. Thus, NVG development in CRVO patients treated with intravitreal bevacizumab injections was associated with an ischaemic CRVO and elevated CRT at the 1-month follow-up; PRN bevacizumab regimens based on CRT or control of macular oedema did not completely prevent NVG development.
Keimyung Author(s)(Kor)
이유현
김유철
Publisher
School of Medicine (의과대학)
Citation
You Hyun Lee and Yu Cheol Kim. (2022). Central retinal thickness changes and risk of neovascular glaucoma after intravitreal bevacizumab injection in patients with central retinal vein occlusion. Sci Rep, 12(1), 2051. doi: 10.1038/s41598-022-06121-x
Type
Article
ISSN
2045-2322
Source
https://www.nature.com/articles/s41598-022-06121-x
DOI
10.1038/s41598-022-06121-x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44219
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.