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Alterations of Functional Connectivity in Patients With Restless Legs Syndrome

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Author(s)
Kang Min ParkKeun Tae KimKyung Wook KangJung A ParkJong-Geun SeoJiyoung KimHyeyeon ChangEun Young KimYong Won Cho
Keimyung Author(s)
Kim, Keun TaeCho, Yong Won
Department
Dept. of Neurology (신경과학)
Journal Title
J Clin Neurol
Issued Date
2022
Volume
18
Issue
3
Keyword
restless legs syndromebrainmagnetic resonance imaging
Abstract
Restless legs syndrome (RLS) is a common neurological illness marked by a strong desire to move one’s legs, usually in association with uncomfortable sensations. Recent studies have investigated brain networks and connectivity in RLS. The advent of network analysis has greatly improved our understanding of the brain and various neurological disorders. A few studies have investigated alterations in functional connectivity in patients with RLS. This article reviews functional connectivity studies of patients with RLS, which have identified significant alterations relative to healthy controls in several brain networks including thalamic, salience, default-mode, and small-world networks. In addition, network changes related to RLS treatment have been found, including to repetitive transcranial magnetic stimulation, transcutaneous spinal cord direct-current stimulation, and dopaminergic drugs. These findings suggest that the underlying pathogenesis of RLS includes alterations in the functional connectivity in the brain and that RLS is a network disorder.
Keimyung Author(s)(Kor)
김근태
조용원
Publisher
School of Medicine (의과대학)
Citation
Kang Min Park et al. (2022). Alterations of Functional Connectivity in Patients With Restless Legs Syndrome. J Clin Neurol, 18(3), 290–297. doi: 10.3988/jcn.2022.18.3.290
Type
Article
ISSN
2005-5013
Source
https://thejcn.com/search.php?where=aview&id=10.3988/jcn.2022.18.3.290&code=0145JCN&vmode=FULL
DOI
10.3988/jcn.2022.18.3.290
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44249
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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