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Low-dose clozapine monotherapy for recurrent non-suicidal self-injury: A case report

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Author(s)
Jae-Won YangSung-Won JungHojun Lee
Keimyung Author(s)
Jung, Sung WonLee, Ho Jun
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Asian J Psychiatr
Issued Date
2022
Volume
73
Keyword
ClozapineNon-suicidal self-injuryAdolescentsDepressionSuicidal ideation
Abstract
Non-suicidal self-injury (NSSI) is a challenging issue in clinical settings. In the present case series, we report two female adolescents with recurrent depression and NSSI. Numerous approaches, such as anti-depressants, anti-psychotics, and even electroconvulsive therapy, were not effective. Clozapine has been implemented in a broad spectrum of psychiatric disorders, particularly refractory depression, impulse control problems, suicidal ideation, and NSSI. With a low dose (12.5–25 mg) of clozapine, the depressive symptoms and NSSI remarkably improved, and the improvement was sustained over four months after discharge. Low-dose clozapine monotherapy may be a treatment option with refractory depression and NSSI.
Keimyung Author(s)(Kor)
정성원
이호준
Publisher
School of Medicine (의과대학)
Citation
Jae-Won Yang et al. (2022). Low-dose clozapine monotherapy for recurrent non-suicidal self-injury: A case report. Asian J Psychiatr, 73, 103113. doi: 10.1016/j.ajp.2022.103113
Type
Article
ISSN
1876-2018
Source
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1876201822001113
DOI
10.1016/j.ajp.2022.103113
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44297
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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