계명대학교 의학도서관 Repository

Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia

Metadata Downloads
Author(s)
Hee Won ChuehSang Mee HwangYe Jee ShimJae Min LeeHee Sue ParkJoon Hee LeeYoungwon NamNamhee KimHye Lim JungHyoung Soo Choi
Keimyung Author(s)
Shim, Ye Jee
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
Blood Res
Issued Date
2022
Volume
57
Issue
2
Keyword
Hereditary hemolytic anemiaDiagnosisStandard operating procedures
Abstract
Although the prevalence of hereditary hemolytic anemia (HHA) is relatively low in Korea, it has been gradually increasing in recent decades due to increment in the proportions of hemoglobinopathies from immigrants of South East Asia, raising awareness of the disease among clinicians, and advances in diagnostic technology. As such, the red blood cell (RBC) Disorder Working Party (WP), previously called HHA WP, of the Korean Society of Hematology (KSH) developed the Korean Standard Operating Procedures (SOPs) for the diagnosis of HHA in 2007. These SOPs have been continuously revised and updated following advances in diagnostic technology [e.g., flow cytometric osmotic fragility test (FOFT) and eosin-5-maleimide (EMA) binding test], current methods for membrane protein or enzyme analysis [e.g., liquid chromatography-tandem mass spectrometry (LC-MS/MS), ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), high-performance liquid chromatography (HPLC)], and molecular genetic tests using next-generation sequencing (NGS). However, the diagnosis and treatment of HHA remain challenging as they require considerable experience and understanding of the disease. Therefore, in this new Korean Clinical Practice Guidelines for the Diagnosis of HHA, on behalf of the RBC Disorder WP of KSH, updated guidelines to approach patients suspected of HHA are summarized. NGS is proposed to perform prior to membrane protein or enzyme analysis by LC-MS/MS, UPLC-MS/MS or HPLC techniques due to the availability of gene testing in more laboratories in Korea. We hope that this guideline will be helpful for clinicians in making diagnostic decisions for patients with HHA in Korea.
Keimyung Author(s)(Kor)
심예지
Publisher
School of Medicine (의과대학)
Citation
Hee Won Chueh et al. (2022). Korean clinical practice guidelines for the diagnosis of hereditary hemolytic anemia. Blood Res, 57(2), 86–94. doi: 10.5045/br.2022.2021224
Type
Article
ISSN
2288-0011
Source
https://www.bloodresearch.or.kr/journal/view.html?volume=57&number=2&spage=86
DOI
10.5045/br.2022.2021224
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44299
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.