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A Prospective Observational Study of the Recurrence Characteristics of Hunner Lesion After Repeated Transurethral Ablation in Patients With Interstitial Cystitis/Bladder Pain Syndrome

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Author(s)
Kwang Jin KoHye Jin ByunSeokhwan BangKyu-Sung Lee
Keimyung Author(s)
Byun, Hye Jin
Department
Dept. of Urology (비뇨의학)
Journal Title
Int Neurourol J
Issued Date
2022
Volume
26
Issue
3
Keyword
AblationInterstitial cystitisRecurrenceTherapeutics
Abstract
Purpose:
The aim of this study was to investigate the rate and pattern of recurrence for patients with Hunner lesion (HL) type interstitial cystitis/bladder pain syndrome (IC/BPS) after transurethral ablation.

Methods:
This prospective study included 210 patients with HL type IC/BPS. The primary outcomes were the recurrence rate according to three patterns of recurrence: pattern A (according to the relationship with the previous surgical site), pattern B (according to the bladder zone), and pattern C (according to the number of lesions). The secondary outcomes were recurrence-free time after treatment according to pattern A and pattern C.

Results:
The pattern A recurrence rate was 50.8% in the same site (A1), 6.7% at a new site (A2), and 42.5% at mixed sites (A3). The pattern B recurrence rate was 10.5% for the anterior wall, 59.0% for the posterior wall, 69.5% for the lateral wall, and 69.0% for the dome area. Multiple lesions recurred as multiple lesions in 75.8% of cases. The pattern C recurrence rate was 10.8% for C1 (single → single), 6.7% for C2 (single → multiple), 6.7% for C3 (multiple → single) and 75.8% for C4 (multiple → multiple). The recurrence-free time in pattern A was 13 months for A1, 12.5 months for A2, and 8 months for A3, with a significant difference between A1 and A3 (p=0.008). There was no significant difference in recurrence-free time in pattern C, either with single or multiple HLs.

Conclusions:
The distinct recurrence characteristics of HLs was not predictable despite repeated ablations. Complete remission should not be expected because the whole bladder was to have the potential to develop the HLs even after repeated transurethral ablation.
Keimyung Author(s)(Kor)
변혜진
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
2093-6931
Source
https://www.einj.org/journal/view.php?doi=10.5213/inj.2142408.204
DOI
10.5213/inj.2142408.204
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44437
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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