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성인간호연구에서의 생물표지자 ‘텔로미어 길이’의 이해와 활용: 종설연구

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Author(s)
Seolbin HanJihee MinDae-Kwang KimIn Deok KongNahyun Kim
Keimyung Author(s)
Kim, Dae Kwang
Department
Dept. of Medical Genetics (의학유전학)
Dept. of Nursing (간호학)
Journal Title
성인간호학회지
Issued Date
2023
Volume
35
Issue
1
Keyword
TelomereBiomarkerAdultNursingReview
Abstract
Purpose:
This study aimed to provide an overview of telomere length (TL) as an emerging biomarker in adult healthcare. Additionally, some measurement considerations and future directions for its application in adult nursing research were described.

Methods:
A comprehensive literature review was conducted.

Results:
TL is a widely known indicator of aging and aging-related diseases at the molecular level. Throughout the literature, TL has been established as a useful biomarker that is indicative of aging-related diseases such as cancer, metabolic diseases, and psychological distress and their resulting health conditions. The main pathway of TL shortening appears as an interaction between genetic and environmental factors through a mechanism commonly known as oxidative stress and inflammation. TL attrition may be slowed down, stopped, or even lengthened by interventions such as mindfulness, meditation, exercise, lifestyle modifications, and cognitive behavioral therapy, which have been demonstrated to have a positive effect on TL. As these interventions have been widely applied in adult nursing research, the value and scope of adult nursing science can be expanded by using TL in such research.

Conclusion:
TL has been shown to be associated with age-related diseases, which are mainly studied in adult nursing research. Therefore, it is necessary to explore various nursing phenomena using TL as a biomarker through adult nursing research and to develop nursing interventions that have a positive effect on TL.
Alternative Title
The Understanding and Application of Telomere Length as an Emerging Biomarker in Adult Nursing Research: A Review
Keimyung Author(s)(Kor)
김대광
김나현
Publisher
School of Medicine (의과대학)
College of Nursing (간호대학)
Type
Article
ISSN
2288-338X
Source
https://kjan.or.kr/DOIx.php?id=10.7475/kjan.2023.35.1.1
DOI
10.7475/kjan.2023.35.1.1
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44821
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Medical Genetics (의학유전학)
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
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