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습성 나이관련황반변성 환자에서 백내장 수술 및 베바시주맙 주입술

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Author(s)
안재홍김유철강경태
Keimyung Author(s)
Kim, Yu CheolKang, Kyung Tae
Department
Dept. of Ophthalmology (안과학)
Journal Title
Keimyung Med J
Issued Date
2023
Volume
42
Issue
1
Keyword
BevacizumabCataract extractionMacular degeneration
Abstract
This study was design to evaluate the efficacy of cataract surgery with simultaneous intravitreal bevacizumab injection for wet age-related macular degeneration. Of the patients who underwent anti-vascular endothelial growth factor injections, cataract surgery was performed in 24 eyes (control group), and simultaneous intravitreal bevacizumab injection was performed in 27 eyes (bevacizumab group). Best corrected visual acuity, ocular tonometry, anterior chamber inflammation, and central subfield macular thickness were measured at baseline and 1 week, 1 month, 3 months, and 6 months after surgery. The mean central subfield macular thickness increased 1 month postoperatively in the control group (p = 0.02), whereas there was no significant change in the bevacizumab group. When the preoperative and postoperative differences between the two groups were compared at each time point, the mean best corrected visual acuity improved in the bevacizumab group at 3 months after surgery (p = 0.045), and the mean central subfield macular thickness was more decreased in the bevacizumab group at 1 month after surgery compared to that of the control group (p = 0.032). Additional anti-vascular endothelial growth factor injection was performed after surgery at 1.56 ± 2.05 months and 2.52 ± 2.01 months, in the control and bevacizumab groups, respectively (p = 0.047). Simultaneous cataract surgery and intravitreal bevacizumab injection is considered an effective treatment since it reduces central subfield macular thickness in the short term, and it can delay the timing of additional anti-vascular endothelial growth factor injections after surgery.
Alternative Title
The Effect of Intravitreal Bevacizumab Injection in Wet Age-Related Macular Degeneration Patients with Cataract Surgery
Keimyung Author(s)(Kor)
김유철
강경태
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
2733-5380
Source
https://www.e-kmj.org/journal/view.php?number=2274
DOI
10.46308/kmj.2022.00234
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/44927
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2023
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
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