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Comparison of the Effectiveness of Intravitreal Bevacizumab Injections with and without Simultaneous Cataract Surgery in Diabetic Patients with Macular Edema

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Author(s)
Jeeyoung KwakYou Hyun LeeKyung Tae KangYu Cheol Kim
Keimyung Author(s)
Lee, You HyunKang, Kyung TaeKim, Yu Cheol
Department
Dept. of Ophthalmology (안과학)
Journal Title
J Clin Med
Issued Date
2023
Volume
12
Issue
12
Keyword
Irvine–Gass syndromebevacizumabcataract extractiondiabetic retinopathymacular edema
Abstract
Intravitreal bevacizumab (IVB), often injected during cataract surgery, is currently the main treatment for diabetic macular edema. This retrospective study aimed to compare the effectiveness of IVB injections alone and during cataract surgery in patients with diabetic macular edema. We examined 43 eyes in 40 patients who underwent cataract surgery with simultaneous IVB injections 3-12 months after IVB injections alone. Best-corrected visual acuity and central subfield macular thickness (CMT) were measured 1-month post-injection. The CMTs of the same eyes with IVB-only first and combined-treatment procedures later were 384 ± 149 vs. 315 ± 109 μm pretreatment (p = 0.0002), and after 1 month, they were 319 ± 102 vs. 419 ± 183 μm (p < 0.0001). In the IVB-only procedure, 56.1% of eyes had CMT < 300 μm 1 month after the injection compared to 32.5% after the combined treatment. Therefore, on average, when IVB was administered during cataract surgery, CMT increased, whereas after IVB injection alone, it effectively decreased. More prospective trials with large sample sizes are needed to evaluate the effectiveness of IVB injection performed simultaneously with cataract surgery.
Keimyung Author(s)(Kor)
이유현
강경태
김유철
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
2077-0383
Source
https://www.mdpi.com/2077-0383/12/12/4060
DOI
10.3390/jcm12124060
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/45237
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Ophthalmology (안과학)
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