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코로나-19 백신 예방접종 후 이상반응으로 중증응급진료센터를 내원한 환자분석: 다기관 후향적 관찰연구

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Author(s)
Seyeong JoDong Eun LeeHyun Wook RyooYun Jeong KimJungbae ParkJung Ho KimTae Chang JangSang-Chan Jin
Keimyung Author(s)
Jin, Sang Chan
Department
Dept. of Emergency Medicine (응급의학)
Journal Title
J Korean Soc Emerg Med
Issued Date
2024
Volume
35
Issue
1
Keyword
COVID-19 vaccinesVaccinationDrug-related side effects and adverse reactions
Abstract
Objective:
This study aimed to analyze types and rates of symptoms according to vaccine type and to identify the characteristics of patients who visited emergency departments (EDs) with adverse reactions after coronavirus disease 2019 (COVID-19) vaccination.

Mthod:
The medical records of 1,020 patients who visited the EDs of five participating tertiary hospitals from February 26, 2021 to July 31, 2021, and reported adverse reactions after vaccination with a COVID-19 vaccine to the Korean Disease Control and Prevention Agency or diagnosed with a disease code U129 at time of ED discharge were retrospectively analyzed. Symptoms, examinations, treatments received at EDs, and hospital outcomes were compared with respect to vaccine type.

Results:
Of the 1,020 study subjects, 559 received the ChAdOx1-S vaccine, 52 the Ad.26.COV2.S vaccine, 331 the BNT162b2 vaccine, and 77 the mRNA-1273 vaccine. The adenovirus-vectored vaccines (ChAdOx1-S and Ad.26.COV2.S) had the highest myalgia and headache complaint rates during the 24 hours following vaccination. However, the mRNA vaccines (BNT162b2 and mRNA-1273) had the highest chest pain and fever complaint rates at 7 days post-vaccination. Furthermore, 4.7% of the study subjects required hospitalization, and three died during hospitalization.

Conclusion:
Patients who visited EDs with adverse reactions after COVID-19 vaccination had various ages and experienced symptoms that depended on vaccine type. Most patients were discharged following ED symptom management, but caution should be exercised as several patients experienced potentially serious adverse events.
Alternative Title
Analysis of patients visiting emergency departments with adverse reactions after COVID-19 vaccination: a multicenter retrospective study
Keimyung Author(s)(Kor)
진상찬
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
2384-048X
Source
https://www.jksem.org/journal/view.php?number=2860
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/45355
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
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