계명대학교 의학도서관 Repository

Utility of Partitioning of Standard Base Excess in Euglycemic Diabetic Ketoacidosis with Hyperchloremic Acidosis

Metadata Downloads
Author(s)
Sehui KimDae-Lim JeeSuyoun ChunJongyoon Ba다
Journal Title
Keimyung Med J
Issued Date
2024
Volume
43
Issue
1
Keyword
Anion gapDiabetic ketoacidosisHyperchloremiaMetabolic acidosisStandard base excess
Abstract
Euglycemic diabetic ketoacidosis (EDKA) can be difficult to recognize during surgery, particularly when the anion gap (AG) is within the normal range. A 73-year-old female patient with type 2 diabetes mellitus underwent surgical adhesiolysis and enterostomy for intestinal obstruction. The patient showed a normal serum glucose level and hyperchloremic acidosis but had an accumulation of unmeasured anions (UA) detected by partitioning of the standard base excess (SBE). This prompted testing for serum ketones, which confirmed the presence of EDKA during surgery. The calculation of the hyperchloremic base deficit as a percentage of the total acidifying base deficit revealed a significant contribution of hyperchloremic acidosis to the severity of mixed metabolic acidosis. The AG approach can misdiagnose high AG metabolic acidosis (HAGMA) with hyperchloremic acidosis as hyperchloremic acidosis only. Partitioning of the SBE can be useful for detecting UA when both HAGMA and hyperchloremic acidosis are present, and it may help determine the necessity of treating hyperchloremia during EDKA.
Type
Article
ISSN
2733-5380
Source
https://www.e-kmj.org/journal/view.php?number=2295
DOI
10.46308/kmj.2023.00248
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/45420
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2024
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.