계명대학교 의학도서관 Repository

Real-world Prescription Patterns and Patient Satisfaction Regarding Maintenance Therapy of Gastroesophageal Reflux Disease: An Observational, Cross-sectional, Multicenter Study

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Author(s)
Cheal Wung HuhNak Hoon SonYoung Hoon YounDa Hyun JungMin Kyung KimEun Jeong GongKyu Chan HuhSeung Young KimMoo In ParkJu Yup LeeJoong Goo KwonJae Hak KimCheol Min ShinKee Wook JungSu Jin HongHee Man KimSuck Chei ChoiHye-Kyung JungHyun Jin KimKwang Jae Lee
Keimyung Author(s)
Lee, Ju Yup
Department
Dept. of Internal Medicine (내과학)
Journal Title
J Neurogastroenterol Motil
Issued Date
2023
Volume
29
Issue
4
Keyword
Gastroesophageal refluxMaintenanceProton pump inhibitors
Abstract
Background/aims:
Gastroesophageal reflux disease (GERD) is a common chronic gastrointestinal disorder that typically requires long-term maintenance therapy. However, little is known about patient preferences and satisfaction and real-world prescription patterns regarding maintenance therapy for GERD.

Methods:
This observational, cross-sectional, multicenter study involved patients from 18 referral hospitals in Korea. We surveyed patients who had been prescribed proton pump inhibitors (PPIs) for GERD for at least 90 days with a minimum follow-up duration of 1 year. The main outcome was overall patient satisfaction with different maintenance therapy modalities.

Results:
A total of 197 patients were enrolled. Overall patient satisfaction, patient preferences, and GERD health-related quality of life scores did not significantly differ among the maintenance therapy modality groups. However, the on-demand therapy group experienced a significantly longer disease duration than the continuous therapy group. The continuous therapy group demonstrated a lower level of awareness of potential adverse effects associated with PPIs than the on-demand therapy group but received higher doses of PPIs than the on-demand therapy group. The prescribed doses of PPIs also varied based on the phenotype of GERD, with higher doses prescribed for non-erosive reflux disease than erosive reflux disease.

Conclusion:
Although overall patient satisfaction did not significantly differ among the different PPI maintenance therapy modality groups, awareness of potential adverse effects was significantly different between the on-demand and continuous therapy groups.
Keimyung Author(s)(Kor)
이주엽
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
2093-0887
Source
https://www.jnmjournal.org/journal/view.html?doi=10.5056/jnm23088
DOI
10.5056/jnm23088
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/45510
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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