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Sex/Gender Differences in Esophageal Motility Disorders

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Author(s)
Ju Yup Lee
Keimyung Author(s)
Lee, Ju Yup
Department
Dept. of Internal Medicine (내과학)
Journal Title
Korean J Helicobacter Up Gastrointest Res
Issued Date
2024
Volume
24
Issue
3
Keyword
SexGenderEsophagusSpasmAchalasia
Abstract
Esophageal motility disorders are relatively rare and are attributed to an imbalance between the excitatory and inhibitory nerves that innervate the esophagus. These disorders include achalasia, distal esophageal spasms, and jackhammer esophagus. The prevalence of achalasia is equal in men and women; however, lower esophageal hypermotility disorders are slightly more common in women. Women with achalasia experience chest pain more frequently, whereas men tend to have high lower esophageal sphincter pressure. Additionally, women with achalasia respond better to pneumatic balloon dilatation than men. However, research on sex and gender differences in the outcomes of peroral endoscopic myotomy remains insufficient. Future studies should investigate the differences in outcomes, complications, and long-term effects to ensure optimal treatment in men and women with esophageal motility disorders. This research will be useful to develop sex-tailored treatments for esophageal motility disorders.
Alternative Title
식도운동성질환에서 성별차이
Keimyung Author(s)(Kor)
이주엽
Publisher
School of Medicine (의과대학)
Type
Article
ISSN
1738-3331
Source
https://helicojournal.org/journal/view.php?doi=10.7704/kjhugr.2024.0037
DOI
10.7704/kjhugr.2024.0037
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/45826
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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