Age and Clinically Actionable Events in Patients With Implantable Loop Recorders: Analysis of Multicenter Loop Recorder Registry
- Author(s)
- Joo Hee Jeong; So-Ryoung Lee; Il-Young Oh; Myung-Jin Cha; Hong Euy Lim; Hyoung-Seob Park; Pil-Sung Yang; Sung Ho Lee; Junbeom Park; Ki-Hun Kim; Jun-Hyung Kim; Jae-Sun Uhm; Jin Hee Ahn; Jumsuk Ko; Ju Youn Kim; Jaemin Shim
- Keimyung Author(s)
- Joo Hee Jeong; So-Ryoung Lee; Il-Young Oh; Myung-Jin Cha; Hong Euy Lim; Hyoung-Seob Park; Pil-Sung Yang; Sung Ho Lee; Junbeom Park; Ki-Hun Kim; Jun-Hyung Kim; Jae-Sun Uhm; Jin Hee Ahn; Jumsuk Ko; Ju Youn Kim; Jaemin Shim
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- J Cardiovasc Electrophysiol
- Issued Date
- 2025
- Volume
- 36
- Issue
- 1
- Abstract
- Introduction:
Little is known about age and clinical intervention after implantable loop recorder (ILR) insertion. This study investigated the association between age and clinical intervention after ILR implantation.
Methods and Results:
Data were obtained from a multicenter registry of ILR in Korea (2017–2020, n = 795). ILRs were inserted with indications of unexplained syncope, recurrent palpitation, or cryptogenic stroke. The primary outcome was clinically actionable event that was a composite of the newly detected atrial fibrillation (AF), pacemaker or implantable cardioverter defibrillator (ICD) implantation, catheter ablation, and anticoagulation initiation. The mean age was 64.3 years, and the mean follow-up duration was 20.6 months. Clinically actionable events were observed in 322 (40.5%) patients. Compared to younger age (< 50 years), older age (≥ 50 years) showed higher prevalence of newly detected AF (3.7% vs. 15.8%; p = 0.001), pacemaker implantation (11.2% vs. 21.2%; p = 0.022), and initiation of anticoagulation (3.7% vs. 18.6%; p < 0.001). No significant differences were found in ICD implantation (1.9% vs. 1.3%; p = 0.996) or catheter ablation (3.8% vs. 6.0%; p = 0.512). The older age group more frequently experienced clinically actionable events compared to the younger age group (hazard ratio 2.52, 95% confidence interval: 1.86–3.41; p < 0.001). A significant association was found in the increase of age (per 1-year) and the risk of clinically actionable events (adjusted hazard ratio 1.03, 95% confidence interval 1.02–1.04; p < 0.001).
Conclusion:
Advanced age is a significant risk factor for clinical intervention after ILR insertion. ILR should be considered more actively in older patients requiring prolonged rhythm monitoring.
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.