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HbA1c Reductions Following Sleeve Gastrectomy Versus Sleeve Gastrectomy With Proximal Jejunal Bypass: Significant Differences in Diabetic Patients

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Author(s)
Eunhye SeoSeung Wan Ryu
Keimyung Author(s)
Seo, Eun HyeRyu, Seung Wan
Department
Dept. of Nursing (간호학)
Dept. of Surgery (외과학)
Journal Title
J Metab Bariatr Surg
Issued Date
2024
Volume
13
Issue
2
Keyword
Diabetes mellitusHemoglobin A, GlycosylatedBariatric surgeryJejunoileal bypass
Abstract
Sleeve gastrectomy with proximal jejunal bypass (SG with PJB) is often preferred for patients with higher body mass index (BMI) and inadequate glycemic control. This study aimed to compare the outcomes of SG and SG with PJB, focusing on glycemic control and BMI in prediabetic and diabetic patients. Preoperative analysis revealed differences in age and hemoglobin A1c (HbA1c) levels between groups: SG with PJB patients were older (38.72±9.75 vs. 34.93±10.90 years, P=0.002) and had higher HbA1c levels (7.25±1.76 vs. 5.86±0.78%, P<0.001). Patients were stratified into prediabetic and diabetic groups. In the prediabetic group, no preoperative differences were observed between the surgical groups. However, in the diabetic group, patients in the SG with PJB had lower BMI (37.77±5.83 vs. 41.08±8.5 kg/m2, P=0.034) and higher HbA1c levels (7.88±1.72 vs. 6.51±1.37%, P<0.001) compared to the SG, despite stratification. Postoperatively, SG with PJB led to significantly lower BMI at 3 months compared to SG, but this difference was not sustained at 6 and 12 months in the prediabetic group. In diabetic patients, SG with PJB resulted in significantly greater reductions in HbA1c levels compared to SG, even when adjusted for BMI as a covariate. At the 12-month follow-up, although SG with PJB still showed higher HbA1c levels than SG (5.79±0.78 vs. 5.59±0.44%, P=0.031), the difference was smaller compared to the preoperative period, where SG with PJB had significantly higher levels (7.88±1.72 vs. 6.51±1.37%, P<0.001). These findings suggest that SG with PJB may offer superior glycemic control in morbidly obese diabetic patients.
Keimyung Author(s)(Kor)
서은혜
류승완
Publisher
College of Nursing (간호대학)
School of Medicine (의과대학)
Type
Article
ISSN
2508-5956
Source
https://jmbs.org/DOIx.php?id=10.17476/jmbs.2024.13.2.71
DOI
10.17476/jmbs.2024.13.2.71
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/46023
Appears in Collections:
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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