Erythema Multiforme-Like Lesions as the Initial Symptom of Coronavirus Disease 2019 Infection in Infant

Abstract

Cutaneous manifestations in pediatric patients with coronavirus disease 2019 (COVID-19) are generally mild, with chilblains being the most commonly reported. Erythema multiforme (EM)-like lesions are rare, especially as initial or isolated symptoms. We report a case of an infant who presented with widespread EM-like targetoid erythematous papules without other systemic symptoms. Severe acute respiratory syndrome coronavirus 2 infection was confirmed using reverse transcription-polymerase chain reaction. This case highlights the need to consider COVID-19 in infants presenting with acute skin eruptions, even in the absence of typical systemic features.