흰쥐 담즙울체간의 Plasma Membrance, Mitochondria 및 Microsome의 5'-Nucleotidase와 Gamma-Glutamyl Transpeptidase의 활성치

Other Titles
5'-Nucleotidase and Gamma-Glutamyl Transpeptidase Activities in the Cholestatic Rat Liver Plasma Membranes, Mitochondria and Microsomes
Authors
곽춘식김여희문교철
Department
Dept. of Biochemistry (생화학)
Issue Date
1987
Citation
Keimyung Medical Journal, Vol.6(1) : 67-76, 1987
Abstract
Changes in the activities of the following have been studied over a period of forty two days following the ligation of common bile duct in rats: plasma membrane, microsomal, mitochondrial, nuclear and cytosolic 5'-nucleotidase and gamma-glutamyl transpeptidase of cholestatic liver. The activities of alkaline phosphatase in the subcellular fractions of cholestatic liver were also measured. The activities of microsomal and cytosolic 5'-nucleotidase in cholestatic liver markedly elevated between the second and the forty-second days of the operation. However, the plasma membrane, mitochondrial and nuclear5'-nucleotidase activities in the cholestatic liver showed a substantial decrease from three days to forty two days after the ligation of common bile duct. The activities of hepatic microsomal, cytosolic, plasma membrane, mitochondrial and nuclear gtamma-glutamyl transpeptidase drastically increased throughout the experiments. The activities of microsomal and cytosolic alkaline phosphatase in the cholestatic liver strikingly increased during the forty two days following the operation, but the plasma-membrane bound alkaline phosphatase in the cholestatic liver had a significant diminution after the ligation of common bile duct.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14462
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Biochemistry (생화학)
2. Keimyung Medical Journal (계명의대 학술지) > 1987
Keimyung Author(s)
곽춘식; 김여희; 문교철
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