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두경부암의 염색체연구

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Author(s)
장성익최인장송달원김중강
Alternative Author(s)
Chang, Sung IkChoi, In JangSong, Dal WonKim, Joong Gahng
Publication Year
1987
Abstract
The auther was pel'ormed chromosome analysis from the patients with laryngeal cancer and nasopharyngeal cancer with newly development technique for cell segregation by using enzyme treated method. Segregated cells were incubated for overnight and chromosomes were obtained with routine fixation and stainning methods.
The results are summerized as follows
A structural abnormality involving chromosome 1 with break point located on long arm was found in the laryngeal cancer and in the nasopharyngeal cancer break points were found on distal segment of short arm in chromosome 3. The N-RAS and SK oncogenes are located near these segment of chromosome 1 and E-B virus is concerned with nasopharyngeal cancer. It should be confirmed to how develope the cancer in the future.
Alternative Title
Chromosome Analysis on the Head and Neck Tumor
Department
Dept. of Anatomy (해부학)
Dept. of Otorhinolaryngology (이비인후과학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.6(1) : 77-83, 1987
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14463
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