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The Effect of the REM Sleep on Peripheral Vestibular Imbalance

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Affiliated Author(s)
김현아이현아이형
Alternative Author(s)
Kim, Hyun AhYi, Hyon AhLee, Hyung
Journal Title
Keimyung Medical Journal
Issued Date
2010
Keyword
NystagmusREM sleepVestibular imbalance
Abstract
Backgrounds and purpose: While it is known that sleep have influence on emergence of rapid
eye movement (REM), namely saccades including fast component of nystagmus, whether
spontaneous nystagmus due to vestibular imbalance presents during sleep is still unclear. The
purpose of our study was to investigate whether tonic vestibular imbalance appeared as
spontaneous nystagmus during the wakeful state could present during REM sleep.
Methods: Overnight polysomnography (PSG) was performed in 7 patients with spontaneous
nystagmus due to vestibular neuritis (VN) and 7 controls without dizziness or any nystagmus. The
numbers of horizontal saccades were counted, during 3 minutes samples of the alert state before
and after the PSG, and the first and last REM sleep.
Results: All patients with VN showed significantly more saccades (fast phases of spontaneous
nystagmus) towards the side contralateral to their vestibular lesion in the alert state before and
after the PSG compared with control group. By contrast, during REM sleep the patients with VN
showed no preponderance in saccade direction (p<0.05). Some brief nystagmoid jerks showed
during REM sleep in both patients and controls equally and also had no preponderance in direction.
Conclusions: The tonic vestibular imbalance at peripheral level observed during alert state does
not appear at the brainstem level during REM sleep. It is suggested that a de-afferentation of the
peripheral vestibular input to the REM sleep generating areas may explain an absence of
nystagmus during REM sleep in patients with VN.
Department
Dept. of Neurology (신경과학)
Brain Research Institute (뇌연구소)
Publisher
Keimyung University School of Medicine
Citation
Hyun Ah Kim et al. (2010). The Effect of the REM Sleep on Peripheral
Vestibular Imbalance. Keimyung Medical Journal, 29(1), 7–12.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15970
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2010
3. Research Institutues (연구소) > Brain Research Institute (뇌연구소)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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